Wednesday, October 28, 2009

The Basics of Peritoneal Mesothelioma

The Basics of Peritoneal Mesothelioma

Mesothelioma is a very aggressive cancer that is caused by exposure to asbestos. Approximately 20 percent of cancers caused by asbestos are peritoneal mesothelioma. This form of the cancer manifests itself in the mesothelial cells of the abdomen when the asbestos fibers become embedded in the space between the cells. It can take as many as 20 to 50 years for the symptoms of peritoneal mesothelioma to appear. Over these years, the asbestos fibers irritate the parietal layer that covers the stomach cavity and they begin to produce cancer cells. Fluid builds up and tumors eventually form.

What are the Symptoms? Symptoms of peritoneal mesothelioma are swelling and pain in the abdomen, diarrhea or constipation, unexplained weight loss, nausea and vomiting, and the appearance of lumps under the skin in the abdominal area.

How is It Treated? Since this type of cancer is usually diagnosed very late in its development, a positive mesothelioma prognosis is not likely, and treatment options are limited. Chemotherapy and radiation are typically used to threat the cancer, along with medication to provide pain relief. For many patients, surgery is not an option because at the point of discovery, the cancer has already spread too far and the patient's poor health may make him or her too weak to recover from the trauma of surgery.

How Does Exposure to Asbestos Cause Peritoneal Mesothelioma? It is believed that there are two ways that asbestos can get into your system.

1. They can be ingested and then and consequently move through the digestive system into the peritoneal lining.

2. Asbestos fibers can be inhaled and travel to the peritoneal lining through the fluids in the lymphatic system.

Once these fibers get into the system, they become trapped and the body has no way to drive them out.

How Does Someone Get Exposed to Asbestos? There is no test or conclusive way to find out if you have been exposed to asbestos. The only thing you can do is to review your life's history and current living conditions to know if you've ever been at risk for exposure to asbestos. Here are a few of the risk factors.

* Living in an area where asbestos occurs naturally is one factor. Small particles of asbestos can get airborne, making it easy for you to inhale them. You can contact the health department where you live to find out if asbestos is in the local environment. * There used to be many industries that used asbestos regularly. If you ever worked in such a facility, you could have been exposed to it. It is also possible that you may have carried the asbestos fibers home to your family. * Before 1978, a lot of electrical wiring was insulated with asbestos. Asbestos was also woven into clothes and gloves that were worn by those regularly exposed to heat and fire. * Buildings and homes built before 1978 were frequently constructed using material with asbestos in them. Since asbestos is a good insulator, it was often used in floor and ceiling tiles, along with shingles and roofing paper. If any of these things were ever damaged, asbestos fibers could have become airborne.

How to Choose the Best Mesothelioma Clinical Trial

How to Choose the Best Mesothelioma Clinical Trial

You can find out about good mesothelioma clinical trials in different ways. You can enter for clinical trials do so after hearing about them from your doctor. You can also actively look for clinical trials on the Internet or in other places, hoping to find more options for treatment. Some clinical trials are advertised directly to patients.
Information about mesothelioma cancer resources can be obtained from several resources. These resources can be divided into 2 main types: clinical trials lists and clinical trials matching services.

1- Clinical trial lists

These sources give you the names and descriptions of clinical trials of new treatments. If there is a study you are interested in, you will probably be able to find it in a list. The list will often include a description of the study, the criteria for patient eligibility, and a contact person. If you (or your health care providers) are willing and able to read through descriptions of all the studies listed for your cancer type, then a list may be all you need. Some organizations that provide lists can help you narrow the list a little, according to the kind of treatment you are looking for (chemotherapy, immunotherapy, radiation therapy, etc.) and the stage of your cancer.

2- Clinical trials matching services

Over the past few years, several organizations have developed computer-based systems to match patients with studies they may be eligible for. This service is often offered online.

Each may differ somewhat in how it works. Some of the services allow you to search for clinical trials without registering at the site. If you have to register, they usually assure you that your information will be kept confidential. Either way, you will probably have to enter certain details, such as the type of cancer, the stage of the disease, and any previous treatments you may have had. When given this information, these systems can find clinical trials for which you may be eligible, and save you the time and effort of reading descriptions of studies that are not relevant to you. Some groups also allow you to subscribe to mailing lists so that you are informed as new studies open up.

Although they are usually free to users, most clinical trial matching services get paid for listing studies or get a finder's fee from those running the studies when someone enrolls. Because of this, there may be some differences in the way they rank the studies, or the order in which they present the studies to you.

Because different services work differently, be sure you understand how the service you are looking at operates. Ask the following questions. (Note that the answers do not necessarily mean that the service is not worth using.) *Is there a fee for using the service? *Do I have to register to use the service? *Does the service keep my information confidential? *Where does the service get its list of clinical trials? *Does the service rank the studies in any particular order? Is this based on fees they get? *Can I contact the service through the Internet or by telephone?

Examples of clinical trials matching services are:

1- The American Cancer Society Clinical Trials Matching Service: The American Cancer Society helps patients find high quality care in clinical trials that best match their medical needs and personal preferences, while helping researchers study more effective treatments for future patients

The TrialCheck® database, developed and maintained by the Coalition of Cancer Cooperative Groups, is a comprehensive database that includes the Coalition, National Cancer Institute, and industry trials. To our knowledge, this is the most complete matching database of cancer clinical trials available.

The clinical trials information provided by the American Cancer Society is not biased in any way. It is updated every day, as is the contact information that allows patients to get in touch with the doctors and nurses at cancer centers running each of the studies. You can access the TrialCheck at www.cancer.org (click on "Find a Clinical Trial") or through a toll-free number, 1-800-303-5691.

2- The National Cancer Institute (NCI) sponsors most government-funded cancer clinical trials. The NCI has a list of active studies (those currently enrolling patients), as well as some privately funded studies. You can find the list on their Web site at www.cancer.gov/clinicaltrials or by calling 1-800-4-CANCER (1-800-422-6237). You can search the list by the type and stage of cancer, by the type of study (for example, treatment or prevention), or by zip code.

3- The National Institutes of Health (NIH) has an even larger database of clinical trials at www.clinicaltrials.gov, but not all of these are cancer studies.

4- EmergingMed provides a free and confidential matching and referral service for cancer patients looking for clinical trials at www.emergingmed.com, or you can call 1-877-601-8601.

5- CenterWatch (www.centerwatch.com) is a publishing and information services company that keeps a list of both industry-sponsored and government-funded clinical trials for cancer and other diseases.

6- Private companies, such as pharmaceutical or biotechnology firms, may list the studies they are sponsoring on their Web sites or offer toll-free numbers so you can call and ask about them. Some of these firms also offer matching systems for the studies they sponsor. This can be helpful if you are interested in research on a particular experimental treatment and know which company is developing it.

Mesothelioma Prognosis and Care

Mesothelioma Prognosis and Care

Around 2,000 new mesothelioma cases are diagnosed in the US on a yearly basis. Once the patient of mesothelioma is diagnosed, a health care provider will discuss prognosis and will give a result of the impact of cancer on your body. To get rid of poor prognosis, early detection is an absolute must. Recent study has come to the conclusion that mesothelioma symptoms may not make its presence felt until 15 to 30 years after asbestos exposure.
Factors Affecting Prognosis

Diagnosis of mesothelioma normally takes place when it has reached the advanced stages of development. The main reason behind this is that patients take plenty of time in displaying symptoms that are associated with mesothelioma. Apart from that, mesothelioma symptoms are pretty general and quite a number of times resemble less complicated conditions, which makes the process of diagnosing cancer lot tougher.

Because of this, there is hardly a surprise that the prognosis for the majority of patients is not good, but lots of health care providers can advice treatment routines like radiation, chemotherapy and surgery to assist in dealing with the disease.

Stages of Mesothelioma and other factors

Health care providers normally address the cancer with regard to stages. There are four different kinds of stages. The significant factor here is that once mesothelioma cancer has reached the advanced stage, treatment routines are not going to be that effective. If you are diagnosed with stage three or four mesothelioma, surgery is not going to be useful.

Apart from cancer stage and patient age, there are other factors as well that affect prognosis. It includes mesothelioma type, tumor size, tumor location and whether it can be removed through surgery and effects of other symptoms. Malignant mesothelioma is normally diagnosed in people that has attain the age of more than 50. Few individuals already have number of medical issues because of old age, making treatment quite tough.

Complications Associated with Mesothelioma

Some of the complications associated with mesothelioma are mentioned below.

* Digital clubbing * Pain in chest region * Pleural effusion * Ascites * Pleural thickening * Respiratory failure

Kinds of Mesothelioma

Find below information of various kinds of mesothelioma.

* Benign Mesothelioma - It is non-cancerous kinds of mesothelioma. Benign mesothelioma is rare form of cancer and is not fatal if treated on time. It can occur in the body either in form of cysts, tumors or plaques.

* Pleural Mesothelioma - It affects the lung membranes. Pleural mesothelioma is quite identical to lung cancer.

* Perineal Mesothelioma - It affects the heart lining.

* Malignant Mesothelioma - It affects the membranes of certain big cavities.

* Peritoneal Mesothelioma - It affects the abdominal membrane. Peritoneal mesothelioma is the second most occurring form of mesothelioma.

* Pericardial Mesothelioma - The rarest type of mesothelioma cancer which comprises of only 5% of all the mesothelioma cases is pericardial mesothelioma. It has been observed that middle aged people are most likely to develop this type of mesothelioma and men are more vulnerable to this cancer due to their exposure to asbestos.

Mesothelioma Cancer Treatment

Mesothelioma Cancer Treatment

Occupational hazards have always existed in many industries. In the years dating back to the 1940's asbestos was considered a miracle discovery due to the insulation values. Asbestos was used in the retention of heat in ship building, construction, and equipment manufacturing. Today however, asbestos has been recognized as a highly dangerous airborne fiber that lodges in the pleura area of the chest cavity. This fiber bonds with normally healthy cells and corrupts the ongoing natural mutation of cell reproduction. The resulting disease is known as asbestos lung cancer or Mesothelioma. There is little known about asbestos lung cancer or mesothelioma cancer treatment. The standard cancer treatments have had little or no long term success. The three most common types of treatment available are surgical removal of the cancerous tumor, radiation therapy, and chemotherapy. The use of radiation therapy consists of placing concentrations of high intensity x-rays directly to the affected area to shrink tumors and or to kill cancer cells. Up until this last year, the use of radiation therapy has been the norm in combating this terrible disease. Chemotherapy is becoming more popular in the health care field as a treatment for mesothelioma. Chemotherapy is defined as a use of drugs to kill the cancer cells in one particular area. Chemotherapy drugs are general ingested in pill form or are injected into a vein or directly into the affected area. When chemotherapy is applied by injection the most popular method is to deliver the medication straight to the chest cavity or tumor. Chemotherapy has some downsides or side affects. Generally the patient suffers from extreme nausea, hair loss, and exhaustion. Due to the extreme side effects this treatment it is not recommended for extremely ill or physically weak patients. The most invasive form of mesothelioma cancer treatment is surgical removal of the tumor or the entire affected lung. The procedure known as pleurectomy decortication is the removal of the abdominal lining and the tissue that surrounds it. This is done to relieve pain and avoid the fluid build up between the lung and the chest cavity. A more invasive form of surgery is referred to as extrapleural pneumonectomy. This procedure is designed to remove the lung and the lining along with the diaphragm. Health care professionals have found that a combination of radiation therapy and chemotherapy have increased success by a larger percentage. The combination of different chemotherapy drug types and experimenting with dosages have also increased the survival rate to 9 to 12 month longer that with out the treatment. We all know that as with many forms of cancer there is no cure for this dreaded disease. The health care professionals mentioned in this article are fighting an uphill battle in an attempt to bring a cure to this disease. Many health care professionals believe that any cure that may be derived will come from research and development in the DNA make up of a single human cell.

Wednesday, October 7, 2009

How to Choose the Best Home Care Service For Mesothelioma Patients

How to Choose the Best Home Care Service For Mesothelioma Patients

Much of the care that you are going to get as a mesothelioma cancer patient will be given in an outpatient setting, which includes home care. In many ways, home care for the person with cancer is no different than the home care that is given to people with other kinds of illness.
A mesothelioma patient will need help with diet and nutrition, physical therapy, home health aides, speech and respiratory therapy, personal care, emotional support, volunteer services, pharmacy, support from clergy, and other kinds of care.

Also skilled nursing services involving the use of an oncology nurse specialist, who is an expert in cancer care might be available for home care treatment of the mesothelioma patient. Many of these same services are also offered as part of hospice care.

Some of the home care services that could be provided for the mesothelioma patient are:

- chemotherapy

- immunotherapy or biologic therapy (which use different parts of the body's immune system to fight cancer or lessen the side effects of some cancer treatments)

- blood products

- pain management

- antibiotic treatment

- nutritional support

- anti-emetic therapy (treatment for vomiting)

- hydration (giving of fluids, usually IV or through a feeding tube, for patients who cannot drink enough liquids). These infusion therapies can be given at home by home care agencies.

There are some points that you must consider if you want ton choose the best home agency for your care. You must first of all discuss with your health team to know the types of services you will need. Then you can find agencies that offer those services.

Find out about the accreditation, licensing, and certification of the agencies that you are considering. Also ask questions about your prospective agencies quality of cancer care, the type of experience they have with providing cancer care services, and the skills and training of staff at the agencies you are considering.

There are a number of questions you might ask when you're looking at a home care service:

Certification

Are the home care providers that you are considering Medicare-certified? Medicare-certified programs have met federal requirements for patient care and management. Home care providers are closely supervised and controlled. Medicare certifies only agencies with skilled nursing care. To find a Medicare-approved home health agency, you can visit "Home Health Compare" on the Web at www.medicare.gov. This helpful tool is listed under the search tool "Compare Home Health Agencies in Your Area" on their home page. It gives you names, addresses, and phone numbers of nearby agencies. You can also look at quality measures and compare how well the home care agencies deal with common health problems.

Accreditation

Is the agency you are considering accredited by a nationally recognized accrediting body, such as the Joint Commission? You can look up the agency on the Joint Commission Web site at www.qualitycheck.org. The Joint Commission is an independent, not-for-profit organization that evaluates and accredits health care organizations and programs that volunteer for their review. Accreditation is an important measure in selecting quality health care services. You can ask to see the results of the home care agency's most recent Joint Commission survey.

References

How many years has the agency been serving your community? Can the agency give you references from cancer care professionals, such as an oncologist, oncology nurse, cancer center, or an oncology social worker, who have used this agency? Ask for names and phone numbers. A good agency will give these to you if you ask. Talk to these people about their experiences. You may also wish to check with your local Better Business Bureau, your local Consumer Bureau, or the State Attorney General's office. They can tell you if complaints have been filed against the agency.

Licensure

Is your prospective care provider licensed by your state?Most states require licensing of home health agencies.

Consumer information

Does the agency have written statements that list services (including cancer care services), eligibility requirements, costs and payment procedures, staff job descriptions, and malpractice and liability insurance? Ask that they send you any brochures or other information they can share about their services.

Mesothelioma Treatment - Important Facts About Hospice Care

Mesothelioma Treatment - Important Facts About Hospice Care

Hospice, when it was started, was a concept rooted in the centuries-old idea of offering a place of shelter and rest, or "hospitality" to weary and sick travelers on a long journey. Today, hospice care provides humane and compassionate care for people in the last phases of incurable diseases like people with stage 3 and stage 4 mesothelioma cancer so that they can live their last days on earth as fulfilling and comfortable as possible.
Hospice is a philosophy of care. The hospice philosophy or viewpoint accepts death as the final stage of life. The goal of hospice is to enable patients to continue an alert, pain-free life and to manage other symptoms so that their last days may be spent with dignity and quality, surrounded by their loved ones. Hospice affirms life and does not hasten or postpone death. Hospice care treats the person rather than the disease; it focuses on quality rather than length of life. Hospice care is family-centered care.

The patient and family are the ones making the decisions. Care is provided for the patient and family 24 hours a day, 7 days a week. Hospice care can be given in the patient's home, a hospital, nursing home, or private hospice facility. Most hospice care in the United States is given in the home, with a family member or members serving as the main hands-on caregiver.

Hospice care is meant for the time when your cancer is so advanced that treatment will no longer give you any notable benefit, and you have a limited lifespan of less than six months left to live. Hospice offers you palliative care, which only helps to relive the mesothelioma cancer symptoms and not cure the cancer; its main purpose is to improve your quality of life. You, your family, and your doctor decide together when hospice cares should begin.

Cancer patients do not start hospice care early enough. Sometimes the doctor, patient, or family member will not want to start hospice because he or she thinks it means you're giving up, or that there's no hope. This is not true. If you get better or the cancer goes into remission, you can be taken out of the hospice program and go into active cancer treatment. You can go back to hospice care at a later time, if needed. The hope that hospice brings is the hope of a quality life, making the best of each day during the last stages of advanced illness.

These are some important points about hospice care:

-They are a team of professionals

In most cases, an interdisciplinary health care team manages hospice care. This means that many interacting disciplines work together to care for the patient. Doctors, nurses, social workers, counselors, home health aides, clergy, therapists, and trained volunteers care for you. Each of these people offers support based on their special areas of expertise. Together, they then give you and your loved ones complete palliative care aimed at relieving symptoms and giving social, emotional, and spiritual support.

They offer pain and symptom control

Pain and symptom control helps you to live the remainder of your life as comfortable as possible thus allowing you to stay in control of and enjoy your life. This means that side effects are lowered to an extent that you are as free of pain and symptoms as possible, yet still alert enough to enjoy the people around you and make important decisions.

They offer spiritual support

Hospice care also tends to your spiritual needs. Since people differ in their spiritual needs and religious beliefs, spiritual care is set up to meet your specific needs. It may include helping you to look at what death means to you, helping you say good-bye, or helping with a certain religious ceremony or ritual.

Home care and inpatient care

Although hospice care can be centered in the home, you may need to be admitted to a hospital, extended-care facility, or a hospice inpatient facility. The hospice can arrange for inpatient care and will stay involved in your care and with your family. You can go back to in-home care when you and your family are ready.

Respite care

While you are in hospice, your family and caregivers may need a break, they may need some time away from the chores of taking care of you.. Hospice service may offer them a break through respite care, which is often offered in up to 5-day periods. During this time you will be cared for either in the hospice facility or in beds that are set aside for this in nursing homes or hospitals. Families can plan a mini-vacation, go to special events, or simply get much-needed rest at home while you are cared for in an inpatient setting.

Family conferences

Through regularly scheduled family conferences, often led by the hospice nurse or social worker, family members can stay informed about your condition and what to expect. Family conferences also give you all a chance to share feelings, talk about expectations, and learn about death and the process of dying. Family members can find great support and stress relief through family conferences. Conferences may also be done informally on a daily basis as the nurse or nursing assistant talks with you and your caregivers during their routine visits.

Bereavement care

Bereavement is the time of mourning after a loss. The hospice care team works with surviving loved ones to help them through the grieving process. A trained volunteer, clergy member, or professional counselor provides support to survivors through visits, phone calls, and/or letter contact, as well as through support groups. The hospice team can refer family members and care-giving friends to other medical or professional care if needed. Bereavement services are often provided for about a year after the patient's death as it takes most people about a year to get over the grief of losing a loved one.

Mesothelioma Treatment Options

Mesothelioma Treatment Options

Mesothelioma is a dangerous disease that can is marked by the growth of cancerous cells on the mesothelium. Treatments for this disease can be taken from various treatment centers. But there are many factors involved with the proper treatment options. In this article I am going to discuss some of these treatment options.

Mesothelioma disease can be cured properly if it is diagnosed at an earlier stage, and then there is room for survival. The most important type of mesothelioma cure is surgery. But before taking this step make sure that you have discussed the disease with your doctors. Surgery has been done at the initial stage and is a recommended form of mesothelioma treatment. In this process the cancerous cells will be removed from the affected regions of the body. The process might get complicated in certain situations. The surgery might be the direct cause of malignant forms of mesothelioma as seen on some of the patients.

After surgery, the chemotherapy is the second form of mesothelioma treatment. The treatment procedure of chemotherapy is very simple. These chemicals are designed in such a manner that they are known to act on specific cancerous cells only. The doctor might recommend chemotherapy when surgical procedures do not work out to be feasible for the patient. Chemotherapy might be beneficial to some of the patients, but it does come with lots of disadvantages. The body should properly respond to the chemotherapy. If it does not, the treatment is futile. Doctors who are taking care of the patient always keep a tab on the progress achieved by them.

When chemotherapy is not working as intended, doctors shift to another form of mesothelioma treatment. It is known as the radiation therapy. Specialized rays are used in this procedure to burn away the cancer causing cells. This is an expensive procedure and is usually recommended only during the most advanced stages of the disease. Doctors usually subject the patient to chemotherapy and radiation therapy. It is effective for some of the patients, but for others the situation might remain the same. The above-mentioned treatment options are used in conjunction according to the extent of growth of the cancer cells.

Mesothelioma Clinical Trials - A Good Option?

Mesothelioma Clinical Trials - A Good Option?

Mesothelioma is an insidious form of cancer because of the fact it is often discovered so late that treatment options are simply non-existent. For many people, the only option is to consider clinical trials. The question is whether this is a good option.
What are clinical trials? They are testing periods for new drugs or procedures that may eventually prove effective and be approved by the FDA as a treatment for something. Put another way, they are the process of testing whether a drug or procedure does what it is intended to do. Sometimes they do. Sometimes they don't.

Mesothelioma is a brutally difficult cancer to deal with for a unique reason. The problematic characteristic is it is very hard to find until it is too late for the patient. A person can have the cancer for 10, 20 or 30 years during which it can be treated, but still die of it because it went undetected. Given this problem, there are many different clinical trials going on all the time devoted to Mesothelioma treatments. For example, one related to the Mesomark, which is a promising new blood test that can lead to early detection.

Is it safe to take part in clinical trials? Generally, the answer is that it is safe to do so. A drug company does not just produce a drug and then start testing it on people. It must undergo testing and vetting processes before that happens. Still, clinical trials are undisputedly a form of experiment. The researchers think the drug or procedure being tested will work, but aren't sure. This is, after all, why they have not been approved as of yet. The downside is usually just ineffectiveness, but side effects and rarely even death can occur.

Should you submit to clinical trials if you have Mesothelioma? The decision is entirely up to you. A late stage diagnosis of Mesothelioma is very often fatal, so there may be little choice.